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. 2023 Jul 29;8(1):e10382. doi: 10.1002/lrh2.10382

TABLE 2.

Categorization and current status of research topics on predictive modeling for diarrheal disease.

Primary Category Sub‐category Modeling methods for existing predictive models
Disease forecast All‐cause diarrhea Random Forest, autoregressive integrated moving average (ARIMA/X), seasonal‐auto‐regressive‐integrated‐moving‐average (SARIMA/X), multiplicative Holt‐Winters method, compartmental susceptible‐infected‐recovered‐susceptible (SIRS) model, Parsimony Model, gravity models, Multiple Linear Regression, Random Forest Regression, Support Vector Regression, Gradient Boosting Regression, Extreme Gradient Boosting Regression, Convolutional Neural Network, Neural Network Regression
Cholera SIRS‐like models, data assimilation: ensemble Kalfman filter, individual‐based spatially‐explicit stochastic model, logistic regression, SARIMA, model, auto regression model, multiple regression models
Disease/pathogen detection All‐cause diarrhea Naïve Bayes, linear discriminant analysis, quadratic discriminant analysis, support vector machine, Artificial Neural Network
Viral etiology Random Forest, logistic regression
Bacterial etiology Random Forest, logistic regression
Rotavirus Classification trees
Strain dynamics Rotavirus Fourier analysis
Norovirus Fitness models
Shigella Logistic regression, Neural Network, support vector machines
Outcomes Dehydration Logistic regression/recursive partitioning model
Malnutrition Linear regression
Hospitalization None
Prolonged/persistent diarrhea None
Mortality None
Seasonality Principal‐Component Analysis, K‐means clustering, classification and regression trees
Vaccine Vaccine impact SIS‐ (susceptible‐infectious‐susceptible), SIRS‐like compartmental models, ensemble models, dynamic, deterministic compartmental model, periodic regression models, age‐structured compartmental mode
Vaccine cost‐effectiveness Dynamic model
Vaccine hesitancy Logistic regression, Random Forest, and Neural Networks
Determinants of diarrheal disease burden Classification and Regression Trees (CART)