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. Author manuscript; available in PMC: 2024 Sep 18.
Published in final edited form as: ACS Appl Bio Mater. 2023 Aug 11;6(9):3912–3918. doi: 10.1021/acsabm.3c00574

Figure 1. Hairpin-like siRNA-LSNA characterization.

Figure 1.

(A) Chemical structure of hairpin-like siRNA-LSNA. (B) Agarose gel showing hairpin-like siRNA-LSNA formation. (C) DLS of bare liposomes and hairpin-like siRNA-LSNAs. Error bars represent the standard deviation of 10 measurements. (D) siRNA duplex loading on LSNAs using hybridized (hyb.) and hairpin-like (HP) architecture. Error bars represent the standard deviation of 3 technical replicates. Statistical analysis was performed using an unpaired t-test, where “****” represents a P value of <0.0001.