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(A) Cytotoxicity of hairpin-like siRNA-LSNAs and hairpin-like siRNA-AuSNAs. Error bars represent the standard deviation of 3 biological replicates. (B) LD50 of hairpin-like siRNA-LSNAs and hairpin-like siRNA-AuSNAs, derived from curves in (A). Error bars represent the standard deviation of 3 biological replicates. Statistical analysis was performed using an unpaired t-test, where “****” represents a P value of <0.0001.
