Table 1. Potencies (ED50) and Maximum Efficacies or Effects (Emax) of Norpsilocin and Analogues for HTR in Micea.
| 4-HO-DMTb | 4-HO-NMTb | 4-HO-NET | 4-HO-NPT | 4-HO-NALT | 4-HO-NiPT | 4-HO-NnBT | 4-HO-NtBT | 4-HO-NcHT | 4-HO-NBnT | |
|---|---|---|---|---|---|---|---|---|---|---|
| ED50(mg/kg s.c.) | 0.11 | >30 | 1.4 | 2.9 | 1.1 | 3.3 | >30 | >30 | >30 | 1.2 |
| C.I. (95%) | 0.09–0.19 | 0.9–2.4 | 2.7–3.1 | 0.9–1.3 | 2.6–4.4 | 1.0–1.5 | ||||
| Emax(HTR events/30 min) | 23 | 39.8 | 52.1 | 76.6 | 27.5 | 26.1 |
a
Data are expressed as means, with 95% confidence intervals below.
b
Data for psilocin (4-HO-DMT) and norpsilocin (4-HO-NMT) are from a previously published report which used identical testing conditions.5