Skip to main content
. 2023 Dec 22;15(2):328–336. doi: 10.1021/acschemneuro.3c00646

Table 2. 1 nM [3H]-BU99008 Binding (fmol/mg) in CN and AD Brains Alone (Total) and in the Presence of Unlabeled 1 μM SMBT-1a.

  young CN
 EOAD
region of interest total binding + SMBT-1 % displaced total binding + SMBT-1 % displaced
temporal lobe 51 24 53 77 44 43
frontal lobe 36 16 56 72 32 55
a

CN, cognitively normal control; EOAD, early-onset Alzheimer′s disease (<65 years); young CN < 65 years.