Table 2.
Biochemical characteristics in 276 controls and 519 stable angina or ST elevation myocardial infarction patients
Parameters | Controls | STEMI | Stable angina | p-valuea | p-valueb | p-valuec |
---|---|---|---|---|---|---|
No. | 276 | 138 | 381 | |||
Fasting sugar (mg/dL) | 96.1 ± 31.5 | 168.3 ± 80.1 | 136.6 ± 69.9 | < 0.0001 | < 0.0001 | <0.0001 |
HbA1C (%) | 5.7 ± 0.7 | 7.0 ± 1.9 | 6.9 ± 1.7 | < 0.0001 | < 0.0001 | 0.789 |
Total cholesterol (mg/dL) | 157.2 ± 32.3 | 181.5 ± 42.6 | 176.3 ± 45.3 | < 0.0001 | < 0.0001 | 0.241 |
Triglyceride (mg/dL) | 84.0 (63.0 - 116.5) | 127.0 (86.8 - 197.5) | 118.0 (90.0 - 179.0) | < 0.0001 | < 0.0001 | 0.329 |
HDL-cholesterol (mg/dL) | 54.7 ± 15.3 | 37.0 ± 12.0 | 40.8 ± 11.0 | < 0.0001 | < 0.0001 | 0.001 |
LDL-cholesterol (mg/dL) | 90.9 ± 27.1 | 110.8 ± 36.0 | 104.0 ± 38.4 | < 0.0001 | < 0.0001 | 0.070 |
Uric acid (mg/dL) | 4.7 ± 1.9 | 6.8 ± 2.0 | 6.5 ± 2.2 | < 0.0001 | < 0.0001 | 0.348 |
BUN (mg/dl) | 12.0 (9.0 - 15.0) | 18.1 (15.6 - 23.7) | 17.2 (13.5 - 22.1) | < 0.0001 | < 0.0001 | 0.092 |
Creatinine (mg/dl) | 0.8 ± 0.5 | 1.5 ± 0.9 | 1.4 ± 1.1 | < 0.0001 | < 0.0001 | 0.534 |
eGFR (ml/min/1.73m2) | 124.2 ± 44.3 | 60.7 ± 24.2 | 66.4 ± 25.9 | < 0.0001 | < 0.0001 | 0.024 |
Hemoglobin (g/dl) | 14.3 ± 1.1 | 14.0 ± 2.4 | 13.6 ± 2.0 | 0.824 | 0.041 | 0.046 |
Albumin (g/L) | 4.2 ± 0.4 | 3.8 ± 0.4 | 4.0 ± 0.4 | < 0.0001 | 0.784 | < 0.0001 |
Total WBC count (109/L) | 6.367 ± 2.754 | 10.957 ± 4.301 | 7.632 ± 2.642 | < 0.0001 | < 0.0001 | < 0.0001 |
Neutrophil count (109/L) | 4057 ± 2618 | 7762 ± 3841 | 4802 ± 2169 | < 0.0001 | 0.0001 | < 0.0001 |
Monocyte count (109/L) | 380 ± 156 | 632 ± 371 | 448 ± 202 | < 0.0001 | < 0.0001 | < 0.0001 |
Lymphocyte count (109/L) | 1761 ± 716 | 2367 ± 1340 | 2118 ± 1004 | < 0.0001 | < 0.0001 | 0.028 |
Creatine kinase-MB (ng/mL) | - | 7.1 (2.4 - 73.9) | 2.4 (1.1 - 7.1) | - | - | < 0.0001 |
Troponin I (ng/mL) | - | 1.1 (0.1 - 6.5) | 0.1 (0.0 - 0.8) | - | - | < 0.0001 |
hs-CRP (mg/L) | 0.2 (0.1 - 0.5) | 3.7 (0.3 - 8.3) | 2.2 (0.8 - 6.2) | < 0.0001 | <0.0001 | 0.325 |
Data are expressed as mean ± SD, or median (interquartile range). STEMI, ST elevation myocardial infarction; HDL, high-density lipoprotein; LDL, low-density lipoprotein; BUN, blood urine nitrogen; eGFR, estimated glomerular filtration rate; WBC, white blood cell; hs-CRP, high sensitivity C-reactive protein. a: Data were compared between ST elevation myocardial infarction patients and controls. b: Data were compared between stable angina patients and controls. c: Data were compared between ST elevation myocardial infarction patients and stable angina patients.