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. 2024 Jan 1;20(3):848–863. doi: 10.7150/ijbs.91154

Figure 3.

Figure 3

DLBCL-derived exosomes regulated macrophages polarization via ENO2. THP-1 macrophages were treated with exosomes from different ENO2 stably transfected DLBCL cells and then macrophages polarization markers were detected. A-B. ENO2 stably transfected DLBCL cells were established. No significant difference was observed in the concentration of exosomes from different stably transfected DLBCL cells. C. mRNA levels of IL-10, TGF-β, IL-12p40, and TNF-α in THP-1 macrophages. D. IL-10 and IL-12p40 levels in supernatant of THP-1 macrophages. E-H. Proportion of CD68+CD206+THP-1 macrophages and quantification analysis. Data were shown as the mean±SD. *p<0.05, **p<0.01, ***p<0.001.