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Forest plot. Cox regression multivariate analysis of the impact of various variables on progression-free survival in patients with HR+/HER2− mBC including A endocrine therapy combined with CDK4/6i (Endocrine + CDK4/6i) or B chemotherapy. HR, hormone receptor; CTCs, circulating tumor cells; cfDNA, cell-free DNA; *p < 0.05, **p < 0.01, ***p < 0.005
