Table 3.

Alpha- and beta-diversity indexes

	CHD men vs CHD women	CHD men vs non-CVD men	CHD women vs non-CVD women	Non-CVD men vs non-CVD women
N	567/112 (men/women)	567/242 (CVD/non-CVD)	112/87 (CVD/non-CVD)	242/87 (men/women)
Alpha diversity
Shannon	0.199	0.007 (lower in CVD)	0.004 (lower in CVD)	0.639
Simpson (1-D)	0.408	0.003 (lower in CVD)	0.005 (lower in CVD)	0.559
Observed_features	0.741	0.871	0.355	0.510
Faith-fd	0.612	0.386	0.421	0.107
Beta diversity
Jaccard	0.001	0.001	0.001	0.001
Bray–Curtis	0.001	0.001	0.001	0.001
Unweighted_unifrac	0.001	0.001	0.001	0.001
Weighted_unifrac	0.001	0.001	0.002	0.002

CHD coronary heart disease, CVD cardiovascular disease, Faith-fd Faith’s phylogenetic diversity