Table 1.
Patient characteristics
PBC (n = 45) | PSC (n = 27) | |
Age (mean, range in years) | 58 (34–78) | 45 (23–68) |
Sex (male / female) | 4/45 | 19/8 |
Fatigue (yes / no) | 32/15 | 15/12 |
Cirrhosis (yes / no) | 12 / 33 | 2 / 25 |
Inflammatory bowel disease (yes / no) | 0 / 45 | 16 / 11 |
Total serum bilirubin (median, range in μmol/l) | 10 (4–98) | 15 (6–37) |
Serum albumin (median, range in g/l) | 42 (31–48) | 42 (33–47) |
Prothrombin time (median, range in sec.) | 12 (10–18) | 13 (11–16) |
Serum ALT activity (median, range in U/l) | 43 (17–484) | 35 (10–662) |
Serum AST activity (median, range in U/l) | 37 (21–241) | 31 (18–338) |
Serum Alkaline Phosphatase (median, range in U/l) | 154 (68–441) | 147 (53–1141) |
Normal values: bilirubin <18 μmol/l, albumin 35–50 g/l, ALT < 41 U/l (male) < 31 U/l (female), AST < 37 U/l (male) < 31 U/l (female), alkaline phosphatase < 117 U/l, prothrombin time < 13 sec.