Scheme 1. Synthesis of 2-morpholino-4-anilinoquinoline derivatives using 2-morpholinoquinolin-4-ol, 1, through the formation of 4-chloro-2-morpholinoquinoline, 2. Reagents and conditions: (a) POCl3, 90 °C; (b) corresponding aniline, ethanol, reflux.
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