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Small EVs from hepatocyte cell line. Cell culture supernatant was fixed and processed for immunogold-based detection of cytochrome P450 2E1 (Cyp2E1, smaller particle size) and asialoglycoprotein 2 (Asgr2, larger particle size) to demonstrate the detection of hepatocyte-derived EVs by this technique. Magnification 150k ×, scale bar 100 nm.
