Table 3.

Unadjusted and Adjusted Hazard Ratios for 1-year and 30-day Mortality or Readmission, by Age Group

	Unadjusted hazard ratio (95% CI)	Interaction P-value	Adjusted hazard ratio (95% CI)	Interaction P-value
	(N=48,711)		(N=45,201)
30-day all-cause mortality
Treated vs. Untreated, age 65–74	0.31 (0.21, 0.45)	0.289	0.42 (0.28, 0.62)	0.284
Treated vs. Untreated, age 75–84	0.39 (0.30, 0.51)		0.48 (0.36, 0.63)
Treated vs. Untreated, age 85+	0.43 (0.35, 0.53)		0.57 (0.46, 0.71)
1-year all-cause mortality
Treated vs. Untreated, age 65–74	0.50 (0.41, 0.60)	0.114	0.65 (0.54, 0.79)	0.264
Treated vs. Untreated, age 75–84	0.63 (0.55, 0.72)		0.79 (0.68, 0.91)
Treated vs. Untreated, age 85+	0.57 (0.50, 0.64)		0.69 (0.61, 0.78)
30-day all-cause readmission
Treated vs. Untreated, age 65–74	0.69 (0.56, 0.84)	0.395	0.88 (0.70, 1.09)	0.856
Treated vs. Untreated, age 75–84	0.82 (0.68, 0.99)		0.92 (0.76, 1.12)
Treated vs. Untreated, age 85+	0.79 (0.68, 0.92)		0.85 (0.72, 1.01)
1-year all-cause readmission
Treated vs. Untreated, age 65–74	0.68 (0.59, 0.79)	0.109	0.83 (0.71, 0.97)	0.630
Treated vs. Untreated, age 75–84	0.81 (0.73, 0.89)		0.90 (0.82, 1.00)
Treated vs. Untreated, age 85+	0.81 (0.73, 0.90)		0.86 (0.77, 0.95)
30-day all-cause mortality or readmission
Treated vs. Untreated, age 65–74	0.64 (0.53, 0.77)	0.719	0.80 (0.65, 0.99)	0.686
Treated vs. Untreated, age 75–84	0.70 (0.60, 0.83)		0.80 (0.67, 0.95)
Treated vs. Untreated, age 85+	0.65 (0.57, 0.75)		0.72 (0.62, 0.84)
1-year all-cause mortality or readmission
Treated vs. Untreated, age 65–74	0.67 (0.58, 0.78)	0.502	0.81 (0.70, 0.95)	0.437
Treated vs. Untreated, age 75–84	0.74 (0.67, 0.82)		0.85 (0.77, 0.94)
Treated vs. Untreated, age 85+	0.71 (0.64, 0.78)		0.77 (0.70, 0.85)

Treated: received BB+RASi, BB-only or RASi-only at hospital discharge; Untreated: received neither BB nor RASi at hospital discharge