Table 3. Performance of Actim and BTNX RDTs at cut-offs of 40 and 80 mg/L using the Afinion as the reference standard.
Estimate | Cut-off of 40 mg/L | Cut-off of 80 mg/L |
---|---|---|
% (95% CI) | % (95% CI) | |
Prevalence of positive CRP | 26.9 (20.0, 35.1) | 11.5 (7.0, 18.1) |
Actim | ||
Sensitivity | 80.0 (64.3, 90.2) | 80.0 (55.3, 93.4) |
Specificity | 90.5 (83.1, 95.1) | 90.4 (83.8, 94.7) |
PPV | 75.7 (60.1, 86.8) | 52.2 (33.0, 70.8) |
NPV | 92.5 (85.4, 96.4) | 97.2 (92.2, 99.2) |
BTNX | ||
Sensitivity | 94.3 (81.7, 98.7) | 86.7 (62.7, 96.8) |
Specificity | 78.9 (69.8, 86.0) | 86.1 (78.7, 91.3) |
PPV | 62.3 (48.9, 74.1) | 44.8 (28.4, 62.4) |
NPV | 97.4 (91.2, 99.5) | 98.0 (93.2, 99.6) |