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. 2024 Jan 19;4(1):e0002727. doi: 10.1371/journal.pgph.0002727

Table 3. Performance of Actim and BTNX RDTs at cut-offs of 40 and 80 mg/L using the Afinion as the reference standard.

PPV: positive predictive value, NPV: negative predictive value.

Estimate Cut-off of 40 mg/L Cut-off of 80 mg/L
% (95% CI) % (95% CI)
Prevalence of positive CRP 26.9 (20.0, 35.1) 11.5 (7.0, 18.1)
Actim
 Sensitivity 80.0 (64.3, 90.2) 80.0 (55.3, 93.4)
 Specificity 90.5 (83.1, 95.1) 90.4 (83.8, 94.7)
 PPV 75.7 (60.1, 86.8) 52.2 (33.0, 70.8)
 NPV 92.5 (85.4, 96.4) 97.2 (92.2, 99.2)
BTNX
 Sensitivity 94.3 (81.7, 98.7) 86.7 (62.7, 96.8)
 Specificity 78.9 (69.8, 86.0) 86.1 (78.7, 91.3)
 PPV 62.3 (48.9, 74.1) 44.8 (28.4, 62.4)
 NPV 97.4 (91.2, 99.5) 98.0 (93.2, 99.6)