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. 2024 Jan 19;10(3):eadg1222. doi: 10.1126/sciadv.adg1222

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Fig. 7. — (A) Isoproterenol (ISO)–treated RM and PC showed a statistically significant decrease in APD₉₀, relative to vehicle [dimethyl sulfoxide (DMSO)]–treated control cultures; the relative decrease in APD₉₀ was higher in PC compared to RM. (B) PC showed a significant decrease in APD₉₀ when treated with verapamil (VER), while an increase was observed in RM. (C) PC showed a significant increase in APD₉₀ in response to dofetilide (DOF), while no significant difference was observed in RM. (D) Flecainide (FLEC)–treated RM and PC both showed a significant increase in APD₉₀. All panels have n = 24 cells. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.