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. 2024 Jan 19;10(3):eadi4162. doi: 10.1126/sciadv.adi4162

Fig. 7. Model of Tat stimulation of TRAF6-mediated NF-κB activation.

Fig. 7.

Tat directly interacts with TRAF6 to promote its ubiquitination and activate NF-κB to further stimulate viral transcription.