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. Author manuscript; available in PMC: 2024 Aug 25.
Published in final edited form as: Sci Immunol. 2023 Aug 25;8(86):eadg0539. doi: 10.1126/sciimmunol.adg0539

Fig. 2. Virus-specific stem-like CD8 T cells are maintained up to 8 weeks following initial PD-1 blockade.

Fig. 2.

(A) LCMV chronically infected mice were treated with αPD-1 every 3 days for 2 weeks. Following treatment cessation, CD8 T cell responses were analyzed at weeks 2, 4, 6, 8, and 10. (B-D) Absolute number of stem-like cells among the LCMV-specific populations indicated above each plot. Data points represent means from 3 pooled experiments ± SEM; n=3-5 mice per group per timepoint; *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****; P ≤ 0.0001; ns, non-significant.