Table 5 .
Association between Biomarkers and Postoperative Delirium Severity
| Biomarker | Increase in Peak CAM-S1 | 95% C.I. |
|---|---|---|
| Plasma GFAP Plasma NFL |
0.60 0.33 |
(−0.02, 1.22) (−0.31, 1.03) |
| Plasma p-Tau181 | 0.60 | (−0.12, 1.32) |
| Plasma Aβ40 | 0.37 | (−0.32,1.06) |
| Plasma Aβ42 | −0.15 | (−0.84,0.53) |
| CSF GFAP | 0.38 | (−0.24, 1.01) |
| CSF NFL | 0.27 | (−0.36, 0.91) |
| CSF p-Tau181 | 0.43 | (−0.21, 1.08) |
| CSF Aβ40 | −0.63 | (−1.28,0.01) |
| CSF Aβ42 | −0.72 | (−1.35,−0.09) |
per 1 SD increase in biomarker
General Linear Models adjusting for sex, age, vascular comorbidity.
Aβ40 = amyloid β40; Aβ42 = amyloid β42; GFAP = glial fibrillary acid protein; NfL = neurofilament light