TABLE 1.

Patient Demographics

Factor	Total	No AE	AE	P
N	100	78	22
Age, mean (SD)	34 (±12)	33 (±13)	35 (±12)	0.51
Sex (%)				0.14
Male	80 (80%)	65 (83%)	15 (68%)
Female	20 (20%)	13 (17%)	7 (32%)
BMI, mean (SD)	25 (±4)	25 (±3)	26 (±5)	0.24
Smoking status (%)				0.19
Current smoker	17 (17%)	16 (21%)	1 (5%)
Former smoker	5 (5%)	4 (5%)	1 (5%)
Nonsmoker	78 (78%)	58 (74%)	20 (91%)
Alcohol use (%)				0.81
Yes	58 (59%)	32 (42%)	8 (38%)
No	40 (41%)	45 (58%)	13 (62%)
Diabetes (%)				0.64
Yes	1 (1%)	1 (1%)	0 (0%)
No	96 (96%)	75 (96%)	21 (96%)
Unknown	3 (3%)	2 (3%)	1 (5%)
HIV/AIDS status (%)				0.41
No	91 (91%)	72 (92%)	19 (86%)
Unknown	9 (9%)	6 (8%)	3 (14%)
Education completed (%)				0.96
None	3 (3%)	2 (3%)	1 (5%)
Primary	44 (44%)	34 (44%)	10 (46%)
Secondary ordinary	42 (42%)	33 (42%)	9 (41%)
Secondary advanced	1 (1%)	1 (1%)	0 (0%)
College/university	10 (10%)	8 (10%)	2 (9%)
Preinjury work (%)*				0.78
Yes	79 (79%)	62 (80%)	17 (77%)
No	21 (21%)	16 (21%)	5 (23%)
Mechanism of injury (%)				0.41
Road traffic injury	84 (85%)	67 (87%)	17 (77%)
Fall	5 (5%)	3 (4%)	2 (9%)
Crush injury	5 (5%)	3 (4%)	2 (9%)
Gunshot	2 (2%)	2 (3%)	0 (0%)
Other	3 (3%)	2 (3%)	1 (5%)
Injury to debridement, mean days (SD)	0.88 (0.3)	0.88 (±0.3)	0.89 (±0.4)	0.83
Gustilo-Anderson classification (%)				0.46
Type I	3 (3%)	3 (4%)	0 (0%)
Type II	22 (22%)	19 (24%)	3 (14%)
Type IIIA	75 (75%)	56 (72%)	19 (86%)
Fixation type (%)				<0.001†
Intramedullary nail	53 (53%)	49 (63%)	4 (18%)
External fixation	46 (46%)	28 (36%)	18 (82%)
Cast	1 (1%)	1 (1%)	0 (0%)
Randomization (%)				0.34
Gentamicin	55 (55%)	33 (42%)	12 (55%)
Saline	45 (45%)	45 (58%)	10 (46%)
Injury to hospital, mean km (SD)	22 (±24)	20 (±14)	32 (±41)	0.030†

^*Includes paid and unpaid work.

^†Statistically significant.