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. 2024 Jan 19;103(3):e36822. doi: 10.1097/MD.0000000000036822

Table 4.

Association of HPV16 E6 gene mutations with clinicopathological features of cervical cancer.

E6 mutations E6 unmutated P value
Total n 19 10
FIGO stage n (%)
 I 14 (73.7) 9 (90.0) .35
 II 1 (5.3) 1 (10.0)
 III 4 (21.1) 0 (0.0)
Pathological type n (%)
 Squamous carcinoma 15 (78.9) 9 (90.0) >.99
 Adenocarcinoma 3 (15.8) 1 (10.0)
 Adenosquamous carcinoma 1 (5.3) 0 (0.0)
Vascular metastasis n (%)
 + 9 (47.4) 5 (50.0) >.99
 − 9 (47.4) 5 (50.0)
 Unknown 1 (5.3) 0 (0.0)
Lymph node metastasis n (%)
 + 5 (26.3) 2 (20.0) >.99
 − 13 (68.4) 8 (80.0)
 Unknown 1 (5.3) 0 (0.0)

FIGO = International Federation of Gynecology and Obstetrics.