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. 2024 Jan 19;103(3):e36822. doi: 10.1097/MD.0000000000036822

Table 5.

Association of HPV16 E7 gene mutations with clinicopathological features of cervical cancer.

E7 mutations E7 unmutated P value
Total n 24 5
FIGO stage n (%)
 I 19 (79.2) 4 (80.0) .42
 II 1 (4.2) 1 (20.0)
 III 4 (16.7) 0 (0.0)
Pathological type n (%)
 Squamous carcinoma 20 (83.3) 4 (80.0) .37
 Adenocarcinoma 3 (12.5) 0 (0.0)
 Adenosquamous carcinoma 1 (4.2) 1 (20.0)
Vascular metastasis n (%)
 + 13 (54.2) 1 (20.0) .44
 − 10 (41.7) 4 (80.0)
 Unknown 1 (4.2) 0 (0.0)
Lymph node metastasis n (%)
 + 7 (29.2) 0 (0.0) .41
 − 16 (66.7) 5 (100.0)
 Unknown 1 (4.2) 0 (0.0)

FIGO = International Federation of Gynecology and Obstetrics.