Table 1.
Patient demographics and characteristics at baseline.
| Characteristics | Patients [192] |
|---|---|
| Age [y] mean [SD] | 44.09 [14.7] |
| Gender female n [%] | 98 [51%] |
| Extension of disease n [%] | |
| Proctitis | 12 [6.2%] |
| Left colitis | 66 [34.4%] |
| Pancolitis** | 114 [59.4%] |
| Disease duration [y] mean [SD] | 11.6 [9.5] |
| Endoscopic activity | |
| Mayo 0 | 66 [34.4] |
| Mayo 1 | 44 [22.9] |
| Mayo 2 | 48 [25.0] |
| Mayo 3 | 34 [17.7] |
| Therapy at baseline | |
| No treatment | 10 [5.2%] |
| 5-ASA | 86 [44.8%] |
| Corticosteroids | 23 [12.0%] |
| Immunosuppressants | 31 [16.1%] |
| Biologics/advanced small molecules | 42 [21.9%] |
| Robarts Histological Index mean [SD] | 9.7 [9.9] |
| Nancy Histological Index mean [SD] | 1.9 [1.4] |
| PHRI mean [SD] | 1.8 [1.4] |
SD, standard deviation; y, years; 5-ASA, 5-aminosalicylate; PHRI, PICaSSO Histological Remission Index.
**Ulcerative colitis extending proximal to the splenic flexure.