Table 2.

Classification of kinase activities by family and fold group, part 2.

Group	Family and PFAM/COG members	Kinase Activity (E.C.)	Representative PDB or gi
Group 3: ferredoxin-like fold kinases 10973 sequences	nucleoside-diphosphate kinase: PF00334 923 sequences	2.7.4.6 Nucleoside-diphosphate kinase	PDB: 2bef
	HPPK: PF01288 609 sequences	2.7.6.3 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase	PDB: 1eqo
	guanido kinases: PF00217 324 sequences	2.7.3.1 Guanidoacetate kinase	PDB: 1bg0
		2.7.3.2 Creatine kinase
		2.7.3.3 Arginine kinase
		2.7.3.5 Lombricine kinase
	histidine kinase: PF00512, COG2172 9117 sequences	2.7.1.37 Protein kinase (Histidine kinase)	PDB: 1i59
		2.7.1.99 [Pyruvate dehydrogenase(lipoamide)] kinase
		2.7.1.115 [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase
Group 4: ribonuclease H-like 2768 sequences	COG0837, PF00349, PF00370, PF00871	2.7.1.1 Hexokinase	PDB: 1dgk
		2.7.1.2 Glucokinase
		2.7.1.4 Fructokinase
		2.7.1.5 Rhamnulokinase
		2.7.1.7 Mannokinase
		2.7.1.12 Gluconokinase
		2.7.1.16 L-ribulokinase
		2.7.1.17 Xylulokinase
		2.7.1.27 Erythritol kinase
		2.7.1.30 Glycerol kinase
		2.7.1.33 Pantothenate kinase
		2.7.1.47 D-ribulokinase
		2.7.1.51 L-fuculokinase
		2.7.1.53 L-xylulokinase
		2.7.1.55 Allose kinase
		2.7.1.58 2-dehydro-3-deoxygalactonokinase
		2.7.1.59 N-acetylglucosamine kinase
		2.7.1.60 N-acylmannosamine kinase
		2.7.1.63 Polyphosphate-glucose phosphotransferase
		2.7.1.85 Beta-glucoside kinase
		2.7.2.1 Acetate kinase
		2.7.2.7 Butyrate kinase
		2.7.2.14 Branched-chain-fatty-acid kinase
		2.7.2.- Propionate kinase
Group 5: TIM β/α-barrel kinase 1119 sequences	PF00224	2.7.1.40 Pyruvate kinase	PDB: 1a49
Group 6: GHMP kinase 885 sequences	COG1685, COG1907, PF00288, PF01971	2.7.1.6 Galactokinase (*)	PDB: 1h72
		2.7.1.36 Mevalonate kinase
		2.7.1.39 Homoserine kinase
		2.7.1.46 L-arabinokinase
		2.7.1.52 Fucokinase
		2.7.1.71 Shikimate kinase
		2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D- erythritol kinase (*)
		2.7.4.2 Phosphomevalonate kinase
Group 7: AIR synthetase-like 1843 sequences	PF00586	2.7.4.16 Thiamine-phosphate kinase	PDB: 1cli
		2.7.9.3 Selenide, water dikinase
Group 8: riboflavin kinase (previously Group 10) 565 sequences	PF01687	2.7.1.26 Riboflavin kinase (*)	PDB: 1nb9
Group 9: dihydroxyacetone kinase (previously Group 17) 197 sequences		2.7.1.29 Glycerone kinase (*)	PDB: 1un9
Group 10: putative glycerate kinase (previously Group 16) 148 sequences	COG2379	2.7.1.31 Glycerate kinase (*)	PDB: 1o0u
Group 11: polyphosphate kinase (previously Group 9) 446 sequences	PF02503	2.7.4.1 Polyphosphate kinase	gi|7465499 [48..730]
Group 12: integral membrane kinases (previously Group 8) 263 sequences	dolichol kinase: PF01879 127 sequences	2.7.1.108 Dolichol kinase	gi|6323655 [349..513]
	undecaprenol kinase 136 sequences	2.7.1.66 Undecaprenol kinase	gi|1705428