Fig. 2. Beck Depression Inventory (BDI-II) scores from 18 patients with recurrent major depressive disorder (rec. MDD) and 28 healthy individuals (HI) across the study phase and 3 study visits.

Box-plot (y-axis) demonstrates the distribution of scores. We found significant differences between groups (F = 30.89, p < 0.001), but no main effect of time and no interaction effect of time x group (F = 1.36, p > 0.1; F = 0.16, p > 0.1).