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. 2024 Jan 19;14:1703. doi: 10.1038/s41598-024-51978-9

Table 1.

Immunity Clock model construction through the stepwise forward method from peritoneal leukocytes of 202 mice.

Step 1 Step 2 Step 3 Step 4
Constant (β0) 83.799 (1.793) 89.263 (1.737) 95.493 (2.315) 105.222 (2.227)
Lymphoproliferation Concanavalin A (β1)  − 0.029*** (0.003)  − 0.018*** (0.003)  − 0.014*** (0.003)  − 0.012*** (0.003)
Phagocytic Index (β2)  − 0.020*** (0.003)  − 0.019*** (0.003)  − 0.018***(0.003)
Natural Killer Activity (β3)  − 0.238*** (0.064)  − 0.212*** (0.062)
Lymphocyte chemotaxis (β4)  − 0.010** (0.004)
R2 63.8% 87.2% 89.6% 90.6%
Adjusted R2 63.3% 75.4% 79.3% 80.9%

Each value shows the estimated coefficient and the standard error for each coefficient is shown in brackets. **p < 0.01, ***p < 0.001. No standardized beta coefficients (β) represent the amount of change in a dependent variable due to a 1-unit change in the independent variable. R2 is a statistical measure of how well the regression predictions approximate the real data points. An R2 of 100% indicates that the regression predictions perfectly fit the data.