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. 2024 Jan 19;147(1):19. doi: 10.1007/s00401-023-02673-y

Fig. 1.

Fig. 1

Proteomic studies performed on DM2-derived skeletal muscle biopsy samples. a STRING analysis of highly downregulated mitochondrial proteins illustrating the strong molecular interaction network, mainly affecting proteins related to OXPHOS complex I, III and IV assembly. b Volcano plot illustrating up- and downregulated proteins. Up- (green) and downregulated (red) mitochondria-associated proteins are highlighted