Table 1.
Demographics and clinical characteristics between OCB-positive and OCB-negative groups.
| Variable | All (n = 94) | OCB− (n = 60) | OCB+ (n = 34) | p | |
|---|---|---|---|---|---|
| Age (years, M, IQR) | AE | 33 (20, 55) | 44 (22, 58) | 30 (20, 40) | 0.070 |
| NMDAR | 23 (17, 32) | 22 (16, 27) | 29 (18, 36) | 0.281 | |
| Female, n (%) | AE | 40 (42.6) | 26 (43.3) | 14 (41.2) | 0.839 |
| NMDAR | 31 (56.4) | 19 (67.9) | 12 (44.4) | 0.080 | |
| Time from symptom onset until treatment, (days, M, IQR) | AE | 17 (10, 31) | 19 (10, 33) | 17 (8, 23) | 0.191 |
| NMDAR | 12 (7, 18) | 11 (7, 16) | 14 (7, 20) | 0.479 | |
| Prodromal symptoms, n (%) | AE | 30 (31.9) | 16 (26.7) | 14 (41.2) | 0.147 |
| NMDAR | 24 (43.6) | 12 (42.9) | 12 (44.4) | 0.906 | |
| Mental behavior disorder, n (%) | AE | 51 (54.3) | 29 (48.3) | 22 (64.7) | 0.126 |
| NMDAR | 34 (61.8) | 17 (60.7) | 17 (63.0) | 0.864 | |
| Epileptic seizure, n (%) | AE | 58 (61.7) | 35 (58.3) | 23 (67.6) | 0.372 |
| NMDAR | 33 (60.0) | 15 (53.6) | 18 (66.7) | 0.322 | |
| Consciousness disorders, n (%) | AE | 26 (27.7) | 13 (21.7) | 13 (38.2) | 0.084 |
| NMDAR | 18 (32.7) | 8 (28.6) | 10 (37.0) | 0.504 | |
| Cognitive impairment, n (%) | AE | 44 (46.8) | 26 (43.3) | 18 (52.9) | 0.370 |
| NMDAR | 27 (41.9) | 13 (46.4) | 14 (51.9) | 0.688 | |
| Movement disorders, n (%) | AE | 22 (23.4) | 12 (20.0) | 10 (29.4) | 0.300 |
| NMDAR | 18 (32.7) | 8 (28.6) | 10 (37.0) | 0.504 | |
| Speech dysfunction, n (%) | AE | 13 (13.8) | 6 (10.0) | 7 (20.6) | 0.153 |
| NMDAR | 12 (21.8) | 6 (21.4) | 6 (22.2) | 0.943 | |
| Autonomic nervous dysfunction, n (%) | AE | 32 (34.0) | 11 (18.3) | 21 (61.8) | <0.001 |
| NMDAR | 24 (43.6) | 8 (28.6) | 16 (59.3) | 0.022 | |
| Tumor, n (%) | AE | 10 (10.6) | 7 (11.7) | 3 (8.8) | 0.935 |
| NMDAR | 6 (10.9) | 4 (14.3) | 2 (7.4) | 0.700 | |
| ICU admission, n (%) | AE | 23 (24.5) | 8 (13.3) | 15 (44.1) | 0.001 |
| NMDAR | 16 (29.1) | 4 (14.3) | 12 (44.4) | 0.030 | |
| Abnormal MRI, n (%) | AE | 40 (42.6) | 22 (36.7) | 18 (52.9) | 0.125 |
| NMDAR | 27 (49.1) | 14 (50.0) | 13 (48.1) | 0.891 |
M, median; IQR, interquartile range; NMDAR, NMDAR encephalitis subgroup; OCB−, negative oligoclonal bands; OCB+, positive oligoclonal bands; all of NMDAR encephalitis (n = 55); OCB-negative of NMDAR encephalitis (n = 28); OCB-positive of NMDAR encephalitis (n = 27).