Table 2.
Comparison of the CSF and serum findings between OCB-positive and OCB-negative groups.
| Variable | All (n = 94) | OCB− (n = 60) | OCB+ (n = 34) | p | |
|---|---|---|---|---|---|
| CSF cell count (cell/μL, M, IQR) | AE | 16 (4, 47) | 9 (2, 23) | 32 (17, 86) | <0.001 |
| NMDAR | 21 (10, 75) | 15 (8, 64) | 40 (19, 105) | 0.017 | |
| CSF protein (g/L, M, IQR) | AE | 0.39 (0.27, 0.56) | 0.40 (0.27, 0.54) | 0.39 (0.26, 0.60) | 0.774 |
| NMDAR | 0.37 (0.26, 0.56) | 0.36 (0.26, 0.45) | 0.39 (0.28, 0.60) | 0.235 | |
| CSF albumin (mg/L, M, IQR) | AE | 184.00 (133.78, 244.43) | 198.20 (146.73, 250.38) | 163.00 (103.60, 244.43) | 0.288 |
| NMDAR | 177.10 (117.90, 243.60) | 186.95 (115.15, 233.40) | 169.10 (117.90, 246.90) | 0.993 | |
| CSF IgG (mg/L, M, IQR) | AE | 36.51 (27.27, 54.45) | 35.46 (27.52, 48.12) | 41.32 (26.30, 65.55) | 0.269 |
| NMDAR | 35.84 (27.62, 58.46) | 35.37 (27.74, 49.35) | 40.34 (26.62, 73.90) | 0.350 | |
| Serum albumin (g/L, mean ± SD) | AE | 39.04 ± 5.10 | 39.26 ± 5.09 | 38.69 ± 5.18 | 0.607 |
| NMDAR | 40.07 ± 4.61 | 40.82 ± 4.86 | 39.29 ± 4.30 | 0.221 | |
| Serum IgG (g/L, M, IQR) | AE | 10.60 (8.69, 13.55) | 11.00 (8.52, 12.60) | 10.42 (8.81, 14.78) | 0.841 |
| NMDAR | 10.56 (8.50, 15.21) | 11.10 (8.38, 15.73) | 10.29 (8.72, 14.48) | 0.490 | |
| QAlb (M, IQR) | AE | 4.76 (3.40, 6.43) | 4.79 (3.82, 6.33) | 4.45 (2.65, 6.85) | 0.409 |
| NMDAR | 4.35 (2.73, 6.42) | 4.25 (2.62, 6.02) | 4.36 (2.95, 6.94) | 0.827 | |
| IgG index (M, IQR) | AE | 0.68 (0.54, 0.88) | 0.64 (0.50, 0.82) | 0.78 (0.60, 1.13) | 0.005 |
| NMDAR | 0.75 (0.57, 1.05) | 0.71 (0.53, 0.84) | 0.85 (0.61, 1.31) | 0.026 |
M, median; IQR, interquartile range; SD, standard deviation; NMDAR, NMDAR encephalitis subgroup; OCB−, negative oligoclonal bands; OCB+, positive oligoclonal bands; all of NMDAR encephalitis (n = 55); OCB-negative of NMDAR encephalitis (n = 28); OCB-positive of NMDAR encephalitis (n = 27).