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Recruitment of inflammatory cells from blood vessels (C) to lung tissue (B) to BAL (A) as a function of time after intranasal infection with 107 S. pneumoniae cells. Cell populations (mean ± SEM) in blood and BAL fluid were counted, and neutrophils in lung homogenate were measured by quantifying MPO. ∗, P < 0.05 compared with preinfection values; +, P < 0.01 compared with preinfection values.
