Table 2.
SOD activity of cultured splenocytes' macrophages at different intervals post SPPV immunization
Time post treatment | Treatment | ||
Placebo | Inac.SPPV | Atenu. SPPV | |
12 h | 13.3 ± 1.65 | 13.6 ± 1.22 | 12.8 ± 1.35 |
3 d | 12.5 ± 2.8 | 10.82 ± 2.21 | 133 ± 23.1** |
6 d | 10.2 ± 1.79 | 107.7 ± 25 * | 143.7 ± 38* |
9 d | 52.3 ± 19.1 | 253.3 ± 33.4** | 240.7 ± 42.4 ** |
12 d | 47.6 ± 8.5 | 266 ± 26.6** | 293 ± 37.1** |
Splenic macrophages were harvested from mice (five/group). Macrophages were cultured with LPS (1 μg/ml) for 48 h and SOD was measured in the culture supernatant. SPPV treated mice are significantly different from controls at *P < 0.05 or **P < 0.01.