Table 3.
LIMA UltraSEEK Breast Panel variant list.
| Gene | Coverage | Panel | # of Variants |
|---|---|---|---|
| AKT1 | E17K, L52R | Core | 2 |
| ERBB2 (HER2) | G309A, G309E, S310F, L755R, L755S, L755_T759del, D769H, D769Y, V777L, L869R | Core | 10 |
| ESR1 | A283V, K303R, E380Q, V392I, S463P, V534E, L536R, L536Q, Y537N, Y537S, Y537C, D538G, S576L | Core | 13 |
| FOXA1 | E24K, I176M, I176V, D226N, S250F, F266L | Extended | 6 |
| GATA3 | S93F, S137L, M294K, D336fs17, R365G, P409fs37 | Extended | 6 |
| PIK3CA | N345K, C420R, E542K, E545A, E545K, E545Q, H1047L, H1047R | Core | 8 |
| TP53 | R175H, R213*, Y220C, R248W, R248Q, R273C, R273H | Core | 7 |
| Total Variants | 52 | ||