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. 2024 Jan 20;14:1809. doi: 10.1038/s41598-024-52204-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Heatmaps of the top 30 differentially expressed genes (DEGs) identified in each pairwise comparison: (A) 4T1/wt versus 4T1/Tn⁺, (B) 4T1/wt versus 4T1/Tn⁻, and (C) 4T1/Tn⁻ versus 4T1/Tn⁺. Top DEGs are those with the lower FDR values. Genes and samples were grouped by hierarchical clustering.