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. 2024 Jan 8;10:1297008. doi: 10.3389/fnut.2023.1297008

Table 3.

Baseline characteristics of the lipoprotein subfraction analyzed by HPLC.

Placebo (n = 17) Policosanol (n = 15)
Cholesterol Triglyceride Cholesterol Triglyceride
Total, mg/dL 211.0 ± 21.0 81.2 [58.7–96.9] 207.5 ± 15.5 92.9 [67.0–127.2]
Large CM (Fraction 1), mg/dL 0.09 [0.06–0.16] 0.28 [0.13–0.72] 0.13 [0.07–0.23] 0.28 [0.18–1.22]
CM (Fraction 2), mg/dL 0.07 [0.03–0.12] 0.45 [0.17–1.02] 0.08 [0.04–0.17] 0.54 [0.4–1.79]
Largest VLDL (Fraction 3), mg/dL 0.45 [0.33–0.62] 2.8 [1.3–5.0] 0.59 [0.41–1.12] 3.7 [2.3–9.4]
Very Large VLDL (Fraction 4), mg/dL 1.05 [0.52–1.51] 9.8 [4.5–13.0] 1.22 [0.72–3.18] 11.9 [6.8–21.5]
Large VLDL (Fraction 5), mg/dL 5.8 [5.1–6.7] 16.5 [9.2–23.1] 7.5 [5.8–8.5]* 22.6 [12.0–29.2]
Medium VLDL (Fraction 6), mg/dL 5.3 [4.3–9.0] 12.7 [8.3–17.1] 7.3 [5.0–8.7] 17.0 [12.1–20.0]
Small VLDL (Fraction 7), mg/dL 8.2 [6.3–10.9] 5.5 [4.7–6.0] 8.1 [7.1–10.6] 6.7 [5.1–7.4]
Large LDL (Fraction 8), mg/dL 35.6 ± 5.8 8.1 [7.3–10.1] 33.8 ± 5.9 9.1 [7.6–10.3]
Medium LDL (Fraction 9), mg/dL 55.2 ± 5.5 7.8 [7.2–9.1] 53.3 ± 4.6 8.5 [7.6–9.4]
Medium to small LDL (Fraction 10), mg/dL 24.5 ± 3.6 3.3 [3.0–3.8] 23.6 ± 3.3 3.4 [2.7–4.1]
Small LDL (Fraction 11), mg/dL 7.8 ± 1.1 1.00 [0.91–1.21] 7.4 ± 0.9 1.03 [0.87–1.26]
Very small LDL (Fraction 12), mg/dL 1.3 ± 0.3 0.23 [0.18–1.28] 1.2 ± 0.2 0.21 [0.19–0.3]
Smallest LDL (Fraction 13), mg/dL 1.2 ± 0.2 0.19 [0.17–0.23] 1.2 ± 0.1 0.22 [0.17–0.26]
Largest HDL (Fraction 14), mg/dL 0.9 ± 0.2 0.16 [0.14–0.19] 0.9 ± 0.2 0.17 [0.15–0.23]
Very Large HDL (Fraction 15), mg/dL 3.0 ± 1.5 0.50 [0.37–0.76] 3.1 ± 1.4 0.69 [0.57–0.9]
Large HDL (Fraction 16), mg/dL 15.1 ± 6.1 2.7 [1.9–3.5] 14.9 ± 6.3 3.3 [2.7–4.1]
Medium HDL (Fraction 17), mg/dL 22.0 ± 3.4 3.1 [2.7–3.7] 21.0 ± 3.8 4.0 [3.1–5.8]*
Small HDL (Fraction 18), mg/dL 14.9 ± 1.8 1.9 [1.5–2.1] 14.6 ± 1.8 2.5 [1.8–3.2]
Very Small HDL (Fraction 19), mg/dL 4.8 ± 0.5 0.47 [0.42–0.6] 4.6 ± 0.6 0.64 [0.46–0.94]
Smallest HDL (Fraction 20), mg/dL 1.5 ± 0.1 0.56 [0.52–0.64] 1.5 ± 0.1 0.60 [0.56–0.69]

Values represent the mean ± standard deviation or median with interquartile range. Values of fractions 1–7 of cholesterol and all fractions of triglyceride in both groups were log-transformed prior to analysis. *p < 0.05 vs. cholesterol or triglyceride values in the opposite group. Placebo group, n = 17 and policosanol group, n = 15. CM, chylomicron; VLDL, very low-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; HDL, high-density lipoprotein.