Figure 6.

Comparison of the CNN1 (hold-out approach) and CNN2 (cross-validation approach) models. Data used for the comparison is based only on the individuals used in the test dataset of CNN1. In (A), we present the test dataset’s predicted brain age (y-axis) for both models correlated to chronological age (x-axis). In (B), we present the correlation between the predicted brain age estimated by the two models (CNN1 on the x-axis and CNN2 on the y-axis) in the training (left) and test (right) datasets split by CNN1. In (C), we present the correlation between the brain age difference estimated by the two models (CNN1 on the x-axis and CNN2 on the y-axis) in the training and test datasets.