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. 2024 Jan 8;14:1338260. doi: 10.3389/fphar.2023.1338260

TABLE 4.

Analysis of tumor infiltrating immune cells and hub genes using the Cox proportional hazards model.

Coef HR 95%CI_l 95%CI_u p.value
Age 0.033 1.034 1.011 1.057 0.004
gendermale 0.309 1.362 0.862 2.149 0.185
raceBlack 0.599 1.820 0.725 4.569 0.203
raceWhite 0.187 1.206 0.689 2.109 0.512
stage2 0.784 2.190 0.948 5.058 0.066
stage3 1.027 2.792 1.293 6.031 0.009
stage4 1.403 4.068 1.336 12.385 0.014
Purity −0.616 0.540 0.229 1.276 0.160
B_cell 3.526 34.000 0.189 6129.535 0.183
CD8_Tcell 0.570 1.768 0.055 56.818 0.747
CD4_Tcell −2.946 0.053 0.000 17.706 0.321
Macrophage 7.031 1130.630 15.563 82136.112 0.001
Neutrophil −1.762 0.172 0.000 758.472 0.681
Dendritic −0.163 0.850 0.038 19.121 0.918
CDK1 0.500 1.649 1.054 2.578 0.029
TOP2A −0.133 0.876 0.623 1.231 0.446
AURKB 0.467 1.595 1.016 2.502 0.042
CDCA8 −0.350 0.705 0.443 1.121 0.139
CDC25A −0.169 0.845 0.545 1.308 0.449
CCNE1 0.095 1.100 0.922 1.312 0.289
EZH2 −0.543 0.581 0.348 0.968 0.037
CDC25B −0.137 0.872 0.660 1.152 0.334
RANBP2 0.063 1.066 0.574 1.977 0.840
TPR 0.323 1.381 0.720 2.648 0.331