Table 1.
Basic information of the study subjects.
| Control (n=18) | T2DM (n=41) | T2DM-MCI (n=36) | p | |
|---|---|---|---|---|
| Gender (Male) | 7(38.9%) | 27(65.9%) a | 23(63.9%) a | 0.016 |
| Age (year) | 53.78±12.82 | 56.93±9.22 | 59.78±7.68 | 0.088 |
| Diabetes history (year) | – | 9.90±7.41 | 10.04±6.86 | 0.932 |
| years of education (year) | 14.72±5.69 | 9.34±3.64 a | 8.78±2.26 a | <0.001 |
| Systolic pressure (mmHg) | 129.22±3.62 | 134.46±15.89 | 131.86±15.37 | 0.408 |
| Diastolic blood pressure (mmHg) | 77.33±3.91 | 85.78±10.94 a | 83.36±8.82 a | 0.007 |
| BMI (kg/m2) | 23.41±0.63 | 26.10±3.54 a | 26.25±3.45 a | 0.005 |
| Blood glucose (mmol/l) | 5.48±0.34 | 9.56±2.84 a | 8.92±2.78 a | <0.001 |
| HbA1c(;%) | 5.46±0.27 | 8.60±1.51 a | 8.75±2.13 a | <0.001 |
| ALT(U/L) | 22.00(13.50-27.00) | 18.00(12.00-24.50) | 18.00(12.00-26.00) | 0.755 |
| AST(U/L) | 17.00(15.50-22.50) | 18.00(15.00-23.00) | 18.50(13.00-22.25) | 0.619 |
| Triglycerides (mmol/l) | 1.13±0.58 | 1.70±1.64 | 1.56±0.97 | 0.277 |
| Total cholesterol (mmol/l) | 4.51±0.89 | 4.79±1.67 | 4.20±1.38 | 0.202 |
| HDL-L (mmol/l) | 1.31±0.31 | 1.23±0.55 | 1.17±0.38 | 0.575 |
| LDL-C (mmol/l) | 2.43±0.76 | 2.84±0.90 | 2.52±1.02 | 0.186 |
| Urine (mmol/l) | 5.61(4.83-5.98) | 5.60(4.90-6.60) | 5.80(4.90-6.90) | 0.526 |
| Creatinine (μmol/l) | 70.78±7.45 | 72.52±16.68 | 75.41±23.64 | 0.661 |
| Uric acid (μmol/l) | 271.97±60.25 | 302.47±74.87 | 291.85±82.07 | 0.385 |
| eGFR (ml/min/1.73m2) | 91.90±13.64 | 95.39±19.00 | 89.77±21.40 | 0.447 |
a
versus control, p<0.05.
b
versus T2DM, p<0.05. Significant P values (<0.05) are indicated in bold.