Table 7.
Logistic regression analysis of the associations of NPDR with IL-17A, IL-22, and irisin in T2DM patients.
| Characteristics | Model 1 | Model 2 | ||
|---|---|---|---|---|
| OR (95%CI) | p | OR (95%CI) | p | |
| Age (year) | 0.959(0.854-1.077) | 0.481 | 0.943(0.826-1.076) | 0.380 |
| years of education (year) | 0.960(0.728-1.266) | 0.772 | 1.018(0.752-1.378) | 0.907 |
| HbA1c (%) | – | – | 1.468(0.736-2.929) | 0.276 |
| LDL-C (mmol/L) | – | – | 0.678(0.212-2.161) | 0.511 |
| Average RNFL thickness in left eye (μm) | 1.161(0.967-1.394) | 0.110 | 1.154(0.938-1.418) | 0.175 |
| Average RNFL thickness in right eye (μm) | 0.699(0.532-0.920) | 0.011 | 0.695(0.521-0.928) | 0.013 |
| IL-18 (pg/ml) | 1.002(0.993-1.012) | 0.598 | 1.002(0.992-1.013) | 0.675 |
| CML (pg/ml) | 1.011(1.001-1.021) | 0.030 | 1.012(1.001-1.022) | 0.037 |
| RAGE (pg/ml) | 1.007(1.001-1.013) | 0.017 | 1.007(1.002-1.012) | 0.007 |
| Irisin (pg/ml) | 1.019(0.952-1.092) | 0.585 | 1.022(0.951-1.100) | 0.550 |
Significant P values (<0.05) are indicated in bold.