Table 2.

List of proteomics datasets.

Published year	Coverage	Research objective	Grouping design	Sample source	Sample type	Analytic method	Reference
2013	Untargeted	Pathogenesis	ICP vs Control	Human body	Placenta	iTRAQ LC-MS/MS	(27)
2014	Untargeted	Pathogenesis	ICP vs Control	Human body	Placenta	2D-PAGE MS	(28)
2019	Untargeted	Pathogenesis	Taurocholate vs Control (in vitro cultured tissue model)	In vitro tissue	Placenta	iTRAQ LC-MS/MS	(29)
2019	Targeted	Pathogenesis	ICP vs Control	Human body	Placenta	Immunohistochemistry	(30)
2021	Untargeted	Diagnosis	ICP vs Control	Human body	Serum	DIA LC-MS/MS	(31)
2022	Untargeted	Pathogenesis	ICP vs Control	Human body	Placenta	DIA LC-MS/MS	(32)
2022	Untargeted	Pathogenesis	Chenodeoxycholic acid vs Deoxycholic acid vs Control	Cell line	HTR8 cells	TMT LC-MS/MS	(33)
2023	Untargeted	Pathogenesis	mild ICP vs severe ICP vs Control	Human body	Placenta	DIA LC-MS/MS	(34)
2023	Untargeted	Diagnosis	ICP vs Control	Human body	Plasma exosomes	DIA LC-MS/MS	(35)