Skip to main content
. 1998 Mar;66(3):1063–1069. doi: 10.1128/iai.66.3.1063-1069.1998

TABLE 3.

NO production by macrophages from jirds and mice immunized with BCG-PPDa

dpib TXc ITXd Production by macrophage
Mouse
Jird
Controle BCG-PPDf Controle BCG-PPDf
15 0 4 1.29 ± 0.51 2 ± 0.8 2 ± 0.88 0.65 ± 0.7
LPS 4 1.5 ± 0.39 2.4 ± 0.3 1.7 ± 0.5 0.8 ± 0.5
0 12 NDg 13.4 ± 14 1.3 ± 0 1.12 ± 1.2
LPS 12 5.5 ± 0.8 22.7 ± 6.6 0 0.9 ± 1.28
28 0 4 0.15 ± 0.22 1.16 ± 0.7 1.4 ± 0.6 1.4 ± 0.76
LPS 4 ND 3.33 ± 1.4 0.8 ± 0.5 1.46 ± 0.42
0 12 ND 0.17 ± 0.19 0 0.4 ± 0.44
LPS 12 ND 14.6 ± 4.4 0.3 ± 0.29 0.29 ± 0.38
42 0 4 0.32 ± 0.45 4.6 ± 4.3 0.4 ± 0.5 0.54 ± 0.94
LPS 4 0.63 ± 0.6 4.7 ± 6.7 0.17 ± 0.3 0.8 ± 0.89
0 12 ND 14.3 ± 13.9 0 0
LPS 12 ND 34.8 ± 20.8 0 0
a

Results are expressed as micromolar concentrations of NO2 (means ± standard deviations). 

b

Number of dpi with BCG. 

c

Macrophages were cultured with or without LPS. 

d

Hours of culture with or without LPS. 

e

Uninfected animals. 

f

Animals were infected with BCG and boosted i.p. with PPD, 24 h and 48 h before euthanasia. 

g

ND, not determined.