TABLE 3.
dpib | TXc | ITXd | Production by macrophage
|
|||
---|---|---|---|---|---|---|
Mouse
|
Jird
|
|||||
Controle | BCG-PPDf | Controle | BCG-PPDf | |||
15 | 0 | 4 | 1.29 ± 0.51 | 2 ± 0.8 | 2 ± 0.88 | 0.65 ± 0.7 |
LPS | 4 | 1.5 ± 0.39 | 2.4 ± 0.3 | 1.7 ± 0.5 | 0.8 ± 0.5 | |
0 | 12 | NDg | 13.4 ± 14 | 1.3 ± 0 | 1.12 ± 1.2 | |
LPS | 12 | 5.5 ± 0.8 | 22.7 ± 6.6 | 0 | 0.9 ± 1.28 | |
28 | 0 | 4 | 0.15 ± 0.22 | 1.16 ± 0.7 | 1.4 ± 0.6 | 1.4 ± 0.76 |
LPS | 4 | ND | 3.33 ± 1.4 | 0.8 ± 0.5 | 1.46 ± 0.42 | |
0 | 12 | ND | 0.17 ± 0.19 | 0 | 0.4 ± 0.44 | |
LPS | 12 | ND | 14.6 ± 4.4 | 0.3 ± 0.29 | 0.29 ± 0.38 | |
42 | 0 | 4 | 0.32 ± 0.45 | 4.6 ± 4.3 | 0.4 ± 0.5 | 0.54 ± 0.94 |
LPS | 4 | 0.63 ± 0.6 | 4.7 ± 6.7 | 0.17 ± 0.3 | 0.8 ± 0.89 | |
0 | 12 | ND | 14.3 ± 13.9 | 0 | 0 | |
LPS | 12 | ND | 34.8 ± 20.8 | 0 | 0 |
Results are expressed as micromolar concentrations of NO2− (means ± standard deviations).
Number of dpi with BCG.
Macrophages were cultured with or without LPS.
Hours of culture with or without LPS.
Uninfected animals.
Animals were infected with BCG and boosted i.p. with PPD, 24 h and 48 h before euthanasia.
ND, not determined.