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. 2024 Jan 22;24:15. doi: 10.1186/s40644-023-00634-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — GGNs with different pathological types. (A&B, MIA) A GGN with an average diameter of 9.5 mm could be seen in the upper lobe of right lung (A, red arrows)in a 71-year-old female, and vascular shadows (A, white arrowheads) could be seen inside it. Its score of Lung-RADS and PNI-GARS were 2 and IIIb,respectively.The final pathological diagnosis (B, HE×200) was microinvasive adenocarcinoma (MIA). (C&D, IAC) A GGN with a mean diameter of 11.4 mm could be seen in the lower lobe of right lung (C, red arrows) in a 56-year-old female, and vessels (C, white arrowheads), spiculation (C, red arrowheads ) and pleural indentation signs (C, white arrows) could be seen. Its score of Lung-RADS and PNI-GARS were 2 and IV, respectively. The final pathological diagnosis (D, HE×400) was invasive adenocarcinoma (IAC)