Table 3.
Hazard ratio of mortality from univariate and multivariate cox regression model
| Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR | [95% CI] | p value | HR | [95% CI] | p value | |
| Age | ||||||
| Age > 40 | 1 | |||||
| Age ≤ 40 | 1.33 | [1.14, 1.55] | < 0.001 | |||
| TNBC | ||||||
| Yes | 2.43 | [2.11, 2.79] | < 0.001 | 1.44 | [1.16, 1.79] | < 0.001 |
| Ovary cancer | ||||||
| Yes | ||||||
| First-degree relatives with BC | ||||||
| Yes | 0.7 | [0.51, 0.95] | 0.023 | 0.84 | [0.59, 1.18] | 0.315 |
| T stage | 2.24 | [2.09, 2.41] | < 0.001 | 1.56 | [1.25, 1.95] | < 0.001 |
| N stage | 2.06 | [1.93, 2.19] | < 0.001 | 1.71 | [1.47, 1.75] | < 0.001 |
| Histologic grade | 1.08 | [1.05, 1.11] | < 0.001 | |||
| Endocrine therapy | ||||||
| Yes | 0.37 | [0.33, 0.42] | < 0.001 | 0.53 | [0.44, 0.63] | < 0.001 |
| BRCA test | ||||||
| Low risk | 1 | 1 | ||||
| Not tested | 1.46 | [1.27, 1.68] | < 0.001 | 0.88 | [0.74, 1.05] | 0.165 |
| BRCAx | 1.18 | [0.87, 1.58] | 0.282 | 0.92 | [0.66, 1.27] | 0.611 |
| BRCA mutation | 1.76 | [1.07, 2.89] | 0.026 | 1.02 | [0.59, 1.77] | 0.944 |