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. Author manuscript; available in PMC: 2024 Jan 22.
Published in final edited form as: Crit Care Med. 2012 Feb;40(2):495–501. doi: 10.1097/CCM.0b013e318232da5e
Assay Mean MDC Mean Inter-
Assay CV
Mean Intra-
Assay CV
Manufacturer
Protein C (%) 5% in respect to normal 7.50% 7.00% Helena Laboratories
VEGF 0.81 pg/mL 7.80–9.50% 3.70–6.70% R and D Systems
IL-6 0.36 pg/mL 5.90–7.90% 4.30–4.70% R and D Systems
TNF-alpha 0.60 pg/mL 6.20–7.30% 3.70–4.80% R and D Systems
proCT 0.019 ng/mL < 15% < 10% Brahms
proADM 0.25 nmol/L < 20% < 10% Brahms

MDC: Minimum detectable concentration

CV: Coefficient of Variation

Data in table from data in manufacturer’s manual for respective assays

Ranges provided for assay variation when %CV varied for testing of samples at low and high concentrations

For protein C, standard curve range was 12.5–150% activity and assay detection range was 5 % −200% activity.