Table 3.
Correlations between PFAS Concentration [Log10(X + 1)] in Horses and each Biomarkera
| biomarker |
N |
PFAS β (95% CI) |
||||
|---|---|---|---|---|---|---|
| PFHpA | PFOA | PFUnDA | PFDoDA | PFBS | ||
| sodium (mmol/L) | 26 | −3.30 | −1.98 | 2.39 | 0.49 | 1.46 |
| (−11.88, 5.28) | (−8.45, 4.49) | (−0.88, 5.66) | (−1.78, 2.77) | (−1.02, 3.95) | ||
| potassium (mmol/L) | 26 | −4.96 | −66.67 | 53.16 | −4.79 | 19.33 |
| (−198.13, 188.22) | (−212.46, 79.12) | (−20.43, 79.12) | (−56.00, 46.43) | (−36.59, 75.24) | ||
| total carbon dioxide (mmol/L) | 26 | −378.26 a | −16.80 | 110.83 | 44.28 | 5.52 |
| (−758.30, 1.77) | (−303.61, 270.02) | (−33.95, 255.61) | (−56.47, 145.00) | (−104.48, 115.53) | ||
| creatine kinase (U/L) | 26 | 13.48 | −53.48 b | 18.59 | −4.38 | 19.78 a |
| (−38.59, 65.55) | (−92.78, −14.18) | (−1.25, 38.43) | (−18.18, 9.43) | (4.71, 34.85) | ||
| glucose (mg/dL) | 26 | −2869.64 | 2743.38 | −335.55 | −192.46 | −95.69 |
| (6596.67, 857.38) | (−69.46, 5556.21) | (−1755.44, 1084.34) | (−1180.54, 795.62) | (−1174.50, 983.13) | ||
| calcium (mg/dL) | 26 | −2.27 | −3.49 | 5.39 a | −0.32 | 1.93 |
| (−16.52, 11.98) | (−14,24, 7.27) | (−0.04, 10.82) | (−4.10, 3.45) | (−2.20, 6.06) | ||
| bBlood urea nitrogen (mg/dL) | 26 | −187.74 | −68.39 | 37.08 | −12.75 | 61.91 |
| (−617.09, 241.62) | (−392.43, 255.65) | (−126.49, 200.66) | (−126.58, 101.08) | (−62.37, 186.19) | ||
| creatinine (mg/dL) | 26 | −18.39 | 11.91 | 5.23 | 0.75 | 6.11 |
| (−59.30, 22.52) | (−18.97, 42.78) | (−10.36, 20.82) | (−10.10, 11.59) | (−5.74, 17.95) | ||
| aspartate Aminotransferase (U/L) | 26 | −3581.06 | −3507.56 | 3039.93 | −1599.30 | 1411.47 |
| (−13,041.88, 5879.77) | (−3507.56, 3632.64) | (−564.37, 6644.24) | (−4107.49, 908.89) | (−1327.03, 4149.97) | ||
| total bilirubin (mg/dL) | 26 | 3.29 | −2.12 | 1.51 | 1.09 | −0.45 |
| (−53.03, 59.60) | (−44.62, 40.39) | (−19.95, 23.00) | (−13.84, 16.02) | (−16.76, 15.85) | ||
| GGT (U/L) | 26 | 30.38 | −15.39 | 23.92 | −17.46 a | 2.04 |
| (−35.65, 96.41) | (−65.22, 34.45) | (−1.24, 49.08) | (−34.96, 0.05) | (−17.07, 21.15) | ||
| albumin (g/dL) | 26 | −2.82 | −5.74 | 1.66 | 2.11 | 3.26 |
| (−14.68, 9.04) | (−14.69, 3.21) | (−2.86, 6.18) | (−1.03, 5.26) | (−0.18, 6.69) | ||
| total protein (g/dL) | 26 | 52.81 | −49.95 | 3.62 | 2.33 | 10.69 |
| (−69.44, 175.06) | (−142.22, 42.31) | (−42.96, 50.19) | (−30.08, 34.74) | (−24.69, 46.08) | ||
| globulin (g/dL) | 26 | 61.39 | −29.40 | −0.11 | −4.76 | −0.87 |
| (−34.92, 157.71) | (−102.08, 43.29) | (−36.80, 36.59) | (−30.29, 20.78) | (−28.75, 27.01) | ||
| Albumin/Globulin | ||||||
| ratio | 26 | −37.41 a | 11.41 | 2.92 | 4.76 | 2.04 |
| (−72.81, −2.00) | (−15.31, 38.13) | (−10.57, 16.41) | (−4.63, 14.15) | (−8.21, 12.29) | ||
a
Data in bold indicate a significant association. letters indicate p-values with a = p < 0.05 and b = p < 0.01. β represents the beta coefficients and CI represents the 95% confidence intervals.