Figure 1: Structure of Salinipostin A and Synthesized Phosphonates.

(A) Structure of Salinipostin A and General Mixed Alkyl/Aryl Phosphonate. Salinipostin A (left) is drawn with electrophilic enolphosphate colored red and the mixed alkyl/aryl phosphonate (right) with electrophilic phosphonate group in red.

(B) Synthesis of mixed alkyl/aryl phosphonates and structures of molecules. PPh₃, triphenyl phosphine; I₂, iodine; DCM, dichloromethane; P(OEt)₃, triethyl phosphite; Tf₂O, triflate anhydride; pyr., pyridine; ROH, phenol.

(C) Structures of Short Chain Hexyne-based Phosphonates

(D)Structures of Pentadecane-based Phosphonates