TABLE 1.
Comparison of EECs of PBMCs and levels of FITC-labeled LPS binding by human monocytes for healthy and septic states
| Group (n) | Value for the following
timesa:
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 0 h
|
30
min
|
2 h
|
4 h
|
6 h
|
|||||
| EEC (%) | FITC-labeled LPS binding (%) | EEC (%) | FITC-labeled LPS binding (%) | EEC (%) | FITC-labeled LPS binding (%) | EEC (%) | FITC-labeled LPS binding (%) | EEC (%) | |
| Healthy volunteers (15) | 0.0 | 0.0 | 30.9 ± 4.5 | 60.3 ± 9.0 | 41.5 ± 3.8 | 86.4 ± 4.3 | 49.5 ± 4.5 | 85.1 ± 3.5 | 49.7 ± 4.5 |
| Patients with sepsis (13) | 0.0 | 0.0 | 30.8 ± 4.3 | 48.2 ± 11.1 | 37.3 ± 3.4 | 82.0 ± 2.9 | 41.0 ± 3.4 | 85.4 ± 3.1 | 45.2 ± 5.4 |
| Healthy volunteers + MEM-18 (15) | 0.0 | 0.0 | 0.8 ± 0.3b | 3.2 ± 1.3b | 0.2 ± 0.3b | 4.4 ± 2.3b | 6.5 ± 1.0b | 10.8 ± 4.6b | 8.3 ± 6.0b |
| Patients with sepsis + MEM-18 (13) | 0.0 | 0.0 | 0.8 ± 0.4c | 1.9 ± 0.3c | 0.2 ± 0.3c | 6.8 ± 1.0c | 0.9 ± 0.1c | 13.2 ± 1.0c | 6.5 ± 2.0c |
| Control (8) | 0.0 | 0.0 | 0.7 ± 0.4 | 1.2 ± 0.1 | 1.4 ± 0.1 | 1.5 ± 0.3 | 1.2 ± 0.1 | 1.5 ± 0.4 | 6.8 ± 1.0 |
a
Values are means ± SEM.
b
Significantly different from the values for healthy volunteer (P < 0.05).
c
Significantly different from the values for patients with sepsis (P < 0.05; unpaired t test).