Figure 3.

A. Bar plot of overlapping biological process GO terms from both complete meta-analysis gene lists (Bonferroni-adjusted p-value < 0.05) and retained genes that were previously reported in the four studies. This is addressing the 66 genes that overlap, as seen in the Venn diagram.

Figure 3B. Only Bonferroni corrected p-value < 0.05, enriched gene pathway (orexin receptor pathway) gene list (13 genes) from complete meta-analysis gene list. Up regulation (red) and Down regulation (blue).

Figure 3C. Heat plot of enriched disease from complete meta-analysis gene list. Presented diseases were reduced from 29 to 15 significantly enriched diseases to focus on neurological and sleep-related disorders.