Table 2.
Participant characteristics in the five population level cohorts with whole genome sequencing
| Cohort | Sample size | Age, mean (±SD) | Female, n (%) | FBG (±SD) | Diabetes, n (%) | n of heteroplasmy |
|---|---|---|---|---|---|---|
|
| ||||||
| African American (n = 5456, women 60.8%) | ||||||
|
| ||||||
| ARIC | 241 | 58.4 (6.3) | 144 (59.8) | 100.2 (9.8) | 54 (25.5) | 162 |
| CHS | 705 | 73.8 (5.6) | 445 (63.1) | 97.3 (11.3) | 158 (23.8) | 673 |
| JHS | 3404 | 55.7 (12.8) | 2140 (62.9) | 90.5 (8.9) | 469 (21.3) | 1590 |
| MESA | 1106 | 60.9 (9.6) | 588 (53.1) | 90.1 (10.7) | 174 (15.9) | 968 |
|
| ||||||
| European American (n = 12,051, women 53.7%) | ||||||
|
| ||||||
| ARIC | 3415 | 58.2 (5.9) | 1734 (50.9) | 101.3 (9.6) | 368 (11.1) | 1501 |
| CHS | 2788 | 74.2 (5.7) | 1594 (57.2) | 98.6 (9.8) | 352 (13.1) | 1859 |
| FHS | 3992 | 59.9 (15.7) | 2190 (54.9) | 97.3 (10.2) | 175 (10.5) | 2158 |
| MESA | 1856 | 61.6 (9.8) | 952 (51.1) | 87.1 (9.6) | 95 (5.1) | 1236 |
ARIC, Atherosclerosis Risk in Communities Study; CHS, Cardiovascular Health Study; FHS, Framingham Heart Study; JHS, Jackson Heart Study; MESA, Multi-Ethnic Study of Atherosclerosis. SD, standard deviation