Fig 4. Piscidins do not synergize strongly with ciprofloxacin.
Culture density after overnight growth in the presence of the indicated concentrations of ciprofloxacin and sub-inhibitory concentrations of (A) p1 or p1-Cu2+complex or (B) p3 or p3-Cu2+. Data shown represent the means and standard deviations of at least three samples. Conditions are compared by two-way ANOVA. The comparison between samples containing ciprofloxacin and those containing ciprofloxacin and peptides is shown in black. When comparisons between the apo and holo forms of the peptides are statistically significant, they are shown in grey.. n.p. no peptide, n.s. not significant, * p > 0.05, **** p > 0.0001.