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. 2024 Jan 22;7(4):e202302177. doi: 10.26508/lsa.202302177

Figure S9. DmMIC10b filaments influence the crista architecture in MICOS-deficient mitochondria.

Figure S9.

(A, B, C, D) HeLa cells deficient for MIC10 (MIC10-KO) or MIC60 (MIC60-KO) were transfected with an empty vector or DmMIC10b-FLAG. Cells were chemically fixed and analyzed by transmission EM. (A) Electron micrographs of ultrathin sections. White arrows indicate intramitochondrial filaments. (B) Analysis of the morphology of the mitochondrial ultrastructure. (C) Analysis of the number of CJs. (D) Single plane of an electron tomography dataset. Arrows indicate filaments. Scale bars: 0.5 μm.